BC Biomedical NIBP-1010 Manual de usuario Pagina 18

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Heartfunctions‐physiology
A healthy heart works as a pump, which makes the blood circulate in the body. Blood
is brought from the organs by veins, leading via the upper and the lower vena cava into the
right atrium. By a contraction of the right atrium, the blood is ejected into the right ventricle.
From the right ventricle, the blood is transported via the pulmonary arteries into the lungs,
where it gets rid of carbon dioxide and arterializes. The blood returns from the lungs into the
left atrium via a pulmonary vein, it passes through the valve into the left ventricle, from where
it spreads via the aorta and other arteries throughout the body to supply the tissues with
oxygen and nutrients, and to remove waste materials.
In one minute of a resting state, the heart ejects approximately five litres of blood. If
the heart is in stress, this volume can increase temporarily up to three times. This quantity is
called the cardiac output - CO. For the correct function of the heart it is necessary that the
contractions of the heart muscles are strong enough and synchronized. The contractions are
initialized via electric incitement of the heart muscles; see the chapter below [2.3], [2.4],
[2.5].
Theheart’sconductionsystem‐electrophysiology
The heart muscle’s cells are excitable, just like all the others, which means, that an
adequate stimulus on a membrane induces a response in the form of an action potential.
However, in case of the heart cells, this potential lasts much longer and its course differs in
the working myocardium as well as in different parts of the conduction system - the set of
specific cells, which are capable of
independent generation of electrical impulses
(automatia), thus controlling the heart’s
functioning. The structure, which generates
pulses with the highest frequency, is called the
pacemaker. Via its activity, it determines the
heart rate - HR. In healthy heart, this is the
sinoatrial (SA) node in the right atrium. From
this node, the pulses spread spokewise via the
atriums all the way to the septum between the
atriums and the ventricles, which is made of
valves. The valves function not only as a
Fig. 2.3: The heart’s transmission
(conduction) system [2.6].
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