BC Biomedical NIBP-1010 Manual de usuario descargar pdf (Pagina 20)

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The action potential is accompanied by changes of tension on the membrane; see Fig.

2.4. These are caused by the flow of ions inside and outside of the cell, based on the changes

in the membrane’s permeability for the specific ion. The action potential occurs when the

membrane potential changes very quickly (in 1-3 ms) from approximately -90 mV to +20 or

+25 mV. In this stage, the cell is depolarized. This is followed by a short partial

repolarization, when the membrane potential’s value decreases to +10 or +15 mV. The next

part of the process is only typical for the heart cells and is called the plateau stage. It lasts for

approximately 200 up to 350 ms. Only in its end the cell is fully repolarized and returns to

the polarized state - the membrane potential is approx. -90 mV again.

Fig. 2.4: The transport of ions over the membrane and changes in polarity in the individual

stages of the action potential [2.6].

(mV)

Time (ms)

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BC Biomedical NIBP-1010 Manual de usuario Pagina 20